Pope Sixtus IV called on the architect Baccio Pontelli for the construction of this church at the end of the 15th Century, during a period of peace after the end of the war with the Turks. It was, indeed, dedicated to the Madonna, as a token of thanks for that peace. At the beginning of the 16th Century Bramante added the cloister, which, though modest in itself, lent an effect of size to the church. Among the frescoes present are Raphael's Sybil and Prophets, designed by Raphael but executed by his pupil Timoteo Viti.
- Open Hours: Monday from 10:00 AM to 04:00 PM, Tuesday to Thursday from 09:00 AM to 12:00 PM, Friday from 10:00 AM to 04:00 PM
- Nearest Train: Spagna